On view in Turin, Italy, through March 15, the Zagato: Collectibles and Design Since 1919 exhibit at the Museo Nazionale dell’Automobile “Avv. Giovanni Agnelli” is tailor-made for aficionados of the Milanese carrozzeria Zagato—whose unique design vocabulary has left an indelible mark on the automotive landscape over nearly a century. Honoring the coachbuilder’s 95th anniversary, the exhibit showcases nine significant designs penned for a variety of European automotive marques, from the company’s first decade t…

Scientists discover how tumor cells divide when oxygen-starved

Most cells do not divide unless there is enough oxygen present to support their offspring, but certain cancer cells and other cell types circumvent this rule. Researchers at The Johns Hopkins University have now identified a mechanism that overrides the cells’ warning signals, enabling cancers to continue to divide even without a robust blood supply. In the process, the researchers found that lysosomes — the cell’s protein “recycling c…

On February 5, the Los Angeles–based eyewear brand Dita opened the doors of its first New York flagship store—the 20-year-old brand’s third U.S. flagship and fourth worldwide—on Manhattan’s Lafayette Street. Designed by Tag Front Architecture Studio, the new 900-square-foot, glass-enclosed space exudes the brand’s edgy West Coast-meets-East Coast aesthetic, with exposed-wood ceilings, industrial steel, concrete walls, contemporary Vibia lighting fixtures, and high-end, hand-finished furnishings. Custom Molteni…

When Àni Villas Anguilla opened four years ago, staying at the 10-bedroom vacation rental (split between two separate private villas) was a lesson in decompression. Now, with a state-of-the-art kite-surfing package launching this spring, the quiet Caribbean getaway is as much a destination for thrill seekers as for beach loungers. The seven-day program begins with round-trip private airfare from anywhere in North America via Private Jet Services for up to 14 guests. Over the week, guests will receive more than…

“Often, one biopsy is not enough to definitively rule out prostate cancer,” says study researcher Jonathan Epstein, M.D., director of the Division of Surgical Pathology and a professor of pathology, urology and oncology at the Johns Hopkins University School of Medicine. “Our research finds that by looking for the presence or absence of cancer in a different way, we may be able to offer many men peace of mind without putting them through the pain, bleeding and risk of infection that can come with a repeat…

Opened in January, La Réserve Paris has been hotly anticipated thanks to its revered sister hotels in Geneva and just outside of Saint-Tropez.

Why Go: From its 8th-arrondissement location to its lavish interiors, La Réserve Paris celebrates the prosperity and aesthetics of the 19th century. During Europe’s belle epoque, Paris incited a Beautiful Era of its own when Emperor Napoléon III commissioned Georges-Eugène Haussmann to demolish the city’s medieval core and rebuild. He was to bring air and light into …

The changes made to the new all-wheel-drive and rear-wheel-drive stick-shift versions of the Jaguar 2016 F-Type are subtle, but substantive.

The F-Type is the first Jaguar sports car to use Electric Power Assisted Steering. Jaguar says the system provides power assistance only when needed, reduces fuel consumption, and cuts carbon dioxide emissions. A 770-watt Meridian audio system, keyless entry and ignition, 14-way power seats, and an InControl smartphone integration system are also standard.

All-wheel…

Boeing’s largest passenger jet, the 747-8 can carry more than 450 passengers in a cabin 20 feet wide and more than 200 feet long. Using this massive space as a canvas, Greenpoint Technologies, based in Kirkland, Wash., recently completed work on a 747-8 with a VIP interior for a private owner.

This is the first jet of its kind to be outfitted for personal use, and Greenpoint has released few details about it, declining to name the client or provide photos of the finished product. But the company has release…

New building to serve as “entryway” to Kimmel Cancer Center

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins will use a $65 million gift toward the construction of a new patient care building that will be named for the late Albert P. “Skip” Viragh, Jr., a Maryland mutual fund investment leader and philanthropist. A pancreas cancer patient treated at Johns Hopkins, Mr. Viragh died of the disease in 2003 at age 62.

The Skip Viragh Outpatient Cancer Building is slated for completion in 2017 an…

Listening to the crystal-clear tones of Audemars Piguet’s new Royal Oak Concept RD#1—completely audible from across the room—epitomizes the sort of transcendent moments that can occur at the annual Swiss watch shows. Even though the watch is not a commercial product, and has no future release date announced, to hear it is to know that a page has been turned in the development of the complication. And while the Concept RD#1 may have stolen the show, there were plenty of other significant release…