The Hotel Casa de Sierra Nevada, a boutique Orient-Express Hotel in the city of San Miguel de Allende, Mexico, draws on its natural surroundings to create a distinct experience at its newly unveiled Laja Spa. Named for the river that runs through the city, the Laja Spa offers specialty treatments such as the Detox Herbal Wrap, which uses heated sheets of pure cotton infused with locally grown herbs to draw out toxins from the skin, followed by a honey and salt exfoliation. Each spa treatment utilizes herbs, oils, and natural resources from the area?even stones from the Laja River are heated and used in massages. The spa’s dining room has also fashioned a healthy menu using ingredients grown in San Miguel, so you can continue experiencing the local flavor at your dinner table. (+52.415.152.70.40, www.casadesierranevada.com)

—Stephanie Mazursky