Sneakers are not ordinarily handmade by artisans, but Strange Matter is not an ordinary company. To create sneakers truly worthy of a bespoke wardrobe, the New York–based design studio has introduced the Strange Matter Clean Series, a new line of low-, mid-, and high-top sneakers—all handcrafted in Tuscany.

Made from premium Italian leather and suede, the shoes are sewn using the same techniques used for classic dress shoes, including stitch-and-turn detailing and a fully calfskin-lined construction. After …