Physicians have long assumed that ovarian cancer—one of the deadliest cancers among women—originates in the ovaries. But new research indicates that the disease might begin elsewhere, a breakthrough that could improve mortality and preserve fertility.
“There have always been inconsistencies because ovarian cancer cells don’t resemble the cells normally found in the ovary,” says Robert Kurman, M.D., a gynecologic pathologist at Johns Hopkins. “Usually, cancerous cells resemble the cells in that organ. But for …

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The Hennessy Prestige range represents the pinnacle of luxury in the Cognac category. The newest Prestige offering, Hennessy Paradis Impérial, is made from a blend of more than 100 of the finest eaux-de-vie from the 19th and 20th centuries, aged between 30 and 130 years. As the maison prepares to celebrate its 250th anniversary, we explore the Hennessy legacy with Maurice Richard Hennessy, the global brand ambassador and an eighth-generation family member. 
Being born into on…

The latest small-batch, high-quality liquid gold to emerge from Napa Valley is not a Chardonnay, but a facial serum. Vintner’s Daughter Active Botanical Serum for Face, a multi-correctional oil meant for all skin types, is the brainchild of April Gargiulo, who first learned the lesson that purity of ingredients equals quality on her family’s farm, Gargiulo Vineyards. Growing up prone to acne, she set herself the mission early on to investigate which lotions and creams actually performed as their manufacturers …

Neurologist Bruce Miller calls tau—a floppy, free-form protein—“the holy grail of dementia.” That designation may come as a surprise to anyone who has even a passing interest in the science of end-of-life brain diseases. A different protein, amyloid-beta (Aß), has become famous as the culprit responsible for the so-called senile plaques that gum up the brains of people with Alzheimer’s disease. Yet tau also plays a role in Alzheimer’s, by far the most prevalent type of dementia, and it’s not Aß but tau, escapi…

Ben Zaricor collects American history and identity, in fabric form. He owns one flag that has not just been to the moon—it was “postmarked” on the lunar surface with tire tracks. He owns two banners that flew on the presidential limousine on the day President John F. Kennedy was assassinated in Dallas. Most impressive, he owns a stunning array of flags from the days when the 13 states were represented by that same number of stars. And each banner has rich meaning. Call it historical texture.
Over the course o…

This Saturday, before the Championships at Wimbledon kick off in London, the 2013 Wimbledon men’s doubles champions are playing an exclusive engagement. The brothers Bob and Mike Bryan, alongside Ana Ivanovic, Stan Wawrinka, and Tomas Berdych, have partnered with Approach, a new specialty travel company that offers tennis fans something new. An event organized by Approach will be held on June 21 at London’s Roehampton Club and will allow a group of up to 42 paying customers (from $6,725 per person) to test the…

The latest creations from the jeweler Nicholas Liu borrow a chapter from ancient mythology that recounts the story of Daedalus and his son Icarus. The two escaped captivity by flying away on wings built from feathers and wax. Though warned that his wings would disintegrate if he flew too close to the sun, Icarus ignored good counsel and fell into the sea.
To capture each stage of the journey, from exodus to descent, Liu’s collection ($4,200 to $45,000) uses wing motifs in different states. One pair of earring…

The Championships at Wimbledon have taken place since 1877, crowning renowned players like Pete Sampras, Roger Federer, and the Williams sisters over the last few decades. This year, Magellan Jets’ Centre Court Private VIP Suite Package, which is available throughout the competition (June 23 through July 6), provides exclusive access to tennis’s premier event.
One-day packages include a round-trip charter flight through London City Airport; all-day chauffeured car service; personal ushers to and from reserved…

The visually arresting Senator Manual Winding Skeletonized Edition is one of the latest timepieces from the German watchmaker Glashütte Original. One of the more intriguing decorative techniques in horology (and the watch’s namesake), skeletonization involves removing extraneous material from the plates and bridges of the watch’s movement—providing a clear view of its mechanisms. Glashütte’s artisans then hand engrave what is left of the movement’s plates and bridges with intricate filigree, enhancing the sens…

Rob Kauffman opens the door into his automotive showroom, and it is hard to know what to drool over first. Corvettes, Mustangs, Camaros, Firebirds—250 or so of the greatest expressions of speed, power, and ingenuity Detroit ever produced—glow as if they just rolled off the production line. Some of these cars are in Kauffman’s personal collection; the rest belong to RK Motors, his vintage car dealership in Charlotte, N.C. As Kauffman cuts left and walks toward his personal cars, the first one that commands atte…